Laboratory

Laboratory of Professor Élodie Boisselier

Department

Department of Ophthalmology and Otolaryngology – Head and Neck Surgery, Faculty of Medicine

Funding agency(ies)

Fondation canadienne pour l’Innovation (FCI) – Fondation du CHU de Québec

Manufacturer (model)

Kibron Inc. (DeltaPi – 4x)

Commissioning

2017

Equipment Description

This instrument measures the surface tension of a well in which a lipid monolayer is initially formed. Once stability is reached, an analyte (peptide, protein, drug, etc.) is injected into the subphase, and its interaction with the surface monolayer is monitored over time. This makes it possible to determine interaction synergies. The instrument is equipped with four wells, allowing simultaneous analyses. Kinetics can also be accelerated by stirring with small magnetic stir bars.

In the laboratory, this instrument is commonly used to study the interactions of peptides, proteins, and small molecules with different lipids.

Technical Specifications

• Technique: Wilhelmy plate tensiometer

• Dynamic range: 0–300 mN/m

• Resolution: 10 μN/m

• Up to four simultaneous analyses

  
  

Areas of expertise

• Surface Tension

• Membrane Interactions

  
  

Conditions of Use

This instrument is available to academic and industrial collaborators, depending on the number of users and the availability of a research professional. This technique requires appropriate training and the presence of a research professional.

Rental Fees (CAD)

On-Campus

To be discussed with the person in charge.

Off-Campus (Academic)

To be discussed with the person in charge.

Industry

To be discussed with the person in charge.

Reservations

Élodie Boisselier, Professeure

elodie.boisselier@fmed.ulaval.ca

418-682-7511, poste 84429