Laboratory

Laboratory of Professor Élodie Boisselier

Department

Department of Ophthalmology and Otolaryngology – Head and Neck Surgery, Faculty of Medicine

Funding agency(ies)

Fondation canadienne pour l’Innovation (FCI)

Manufacturer (model)

Brookhaven Instruments Corporation (NanoBrook Omni couplé avec un autotitrateur BI-ZTU)

Commissioning

2016

Equipment Description

This instrument enables the rapid and precise analysis of the size of nanoparticles and proteins using dynamic light scattering (DLS). Unlike other similar instruments, a major advantage of the Omni is the availability of three detection angles, providing greater flexibility depending on the size and nature of the analyte: 15°, 90°, and 173° (backscattering).

In addition, the zeta potential can be determined under different conditions. The instrument is coupled with a BI-ZTU autotitrator, allowing measurements to be performed at different pH values to determine the isoelectric point, for example, or to vary the salinity.

In the laboratory, this instrument is commonly used to analyze gold nanoparticles in aqueous solution. Depending on the type of cuvette used, other solvents may also be suitable.

Technical Specifications

Dynamic Light Scattering (DLS):

• Measurable size range: 0.3 nm to 10 μm

• Temperature range: −5 to 110 °C

• Three measurement angles: 15°, 90°, and 173°

Zeta Potential:

• Compatible with aqueous or organic solvents, including viscous solvents

• Suitable for high salt concentrations

• Suitable for samples close to the isoelectric point

• Compatible with acids, bases, salts, and surfactants

Areas of expertise

• Proteins

• Colloids

• Nanoparticles

• Zeta Potential

• Dynamic Light Scattering (DLS)

  
  

Conditions of Use

This instrument is available to academic and industrial collaborators, depending on the number of users and the availability of a research professional. This technique requires appropriate training and the presence of a research professional.

Rental Fees (CAD)

On-Campus

To be discussed with the person in charge.

Off-Campus (Academic)

To be discussed with the person in charge.

Industry

To be discussed with the person in charge.

Reservations

Élodie Boisselier, Professeure

elodie.boisselier@fmed.ulaval.ca

418-682-7511, poste 84429