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Gel Permeation Chromatography (GPC)
Laboratory
Nanopharmacology and Pharmaceutical Nanoscience
Department
Research Centre of the Centre hospitalier universitaire de Québec – Université Laval (CHUL)
Funding agency(ies)
Fondation canadienne pour l’innovation (FCI – Fonds des leaders John-R.-Evans (FLJR)
Manufacturer (model)
Agilent
Commissioning
2017
Equipment Description
Size Exclusion Chromatography (SEC) is an analytical technique used to characterize polymers in solution. This technique allows the determination of the number-average molar mass (Mn), weight-average molar mass (Mw), and polydispersity index (PDI) of materials. In an SEC column, polymer chains are separated according to their hydrodynamic diameter.
The mobile phase is THF. Measurements are relative to polystyrene standards (hydrophobic) only.
Technical Specifications
2 Resipore Mixed columns, 4.6 × 300 mm
Mobile phase: THF
Detectors: UV–Vis, fluorescence, and refractive index
Polystyrene calibration: 162–364,000 g/mol
Analysis time: 25–45 minutes per measurement
Areas of expertise
Materials Science
Nanotechnology
Drug Delivery
Conditions of Use
Training on the instrument is required, or the instrument must be operated by a research professional. Available to academic and/or industrial collaborators.
Rental Fees (CAD)
On-Campus
$75/hour with assistance from a research professional
Off-Campus (Academic)
$100/hour with assistance from a research professional
Industry
$150/hour with assistance from a research professional
Reservations
Nicolas Bertrand
nicolas.bertrand@pha.ulaval.ca
418 656-2131 # 407042
